Parameters of the 18F-FDG PET/CT associated with the prognostic factors in the initial staging of Breast Cancer

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Published

2019-08-30

How to Cite

Haro Salvatierra, E., Noboa J, A. P., Lupera, H., Terán, F., Troconis, E., & Colmenter Roman, L. F. (2019). Parameters of the 18F-FDG PET/CT associated with the prognostic factors in the initial staging of Breast Cancer. Oncology Journal (Ecuador), 29(2), 97–109. https://doi.org/10.33821/88

Issue

Vol. 29 No. 2 (2019): August- November

Section

Review Articles

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Copyright (c) 2019 Elfa Haro Salvatierra, Adriana P Noboa J, Hernán Lupera, Fernando Terán, Eduardo Troconis, Luis Felipe Colmenter Roman

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

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Authors

  • Elfa Haro Salvatierra Servicio de Medicina Nuclear, SOLCA - Guayaquil.
  • Adriana P Noboa J 1. Centro Radiológico Oncoimagen, Servicio de Tomografía por Emisión de Positrones, Quito. https://orcid.org/0000-0001-6899-4863
  • Hernán Lupera Hospital Metropolitano de Quito, Servicio de Onco-Hematología, Quito
  • Fernando Terán Hospital Metropolitano de Quito, Servicio de Onco-Hematología, Quito
  • Eduardo Troconis Universidad Central de Venezuela, Escuela de Medicina, Venezuela.
  • Luis Felipe Colmenter Roman Centro de Imagen Molecular – Medicina Nuclear, Maracaibo-Venezuela. https://orcid.org/0000-0003-4219-9559

DOI:

https://doi.org/10.33821/88

Keywords:

ERBB-2 RECEPTOR, BREAST NEOPLASIAS, POSITRON EMISSION TOMOGRAPHY

Abstract

Purpose of the review: This article has the following research question: Should biology, histology and phenotype be considered for initial staging of breast cancer? A review of the metabolic study of breast cancer (CM) is performed with the technique of glucose uptake Fluorada 18-Fluoro-2-Deoxy-D-Glucose and its intensity measurement with positron emission tomography (18F-FDG PET / CT).

Recent Findings: 18F-FDG PET / CT can detect metastases that are not visible in other modalities, invasive ductal carcinoma shows a higher uptake than invasive lobular carcinoma. The high uptake of 18F-FDG has been associated with a worse outcome and shorter survival.

Excerpt: Breast cancer is a heterogeneous type of malignancy because several factors affect its behavior and prognosis. Due to this heterogeneity, the optimal treatment and the expected response to treatment may vary substantially for each patient. 18F-FDG PET / CT can provide relevant information on the metabolism, diagnosis and prognosis of breast cancer. Several studies have suggested a correlation between the clinical-pathological characteristics of breast cancer and the metabolic parameters obtained by 18F-FDG PET / CT.

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