Clinical Case: Nodular Sclerosing Angiomatous Splenic Transformation.

Abstract

Introduction: The benign lesion, called angiomatoid nodular sclerosing spleen transformation, is a rare lesion described for the first time in 2004, until the year 2017 there are only 100 cases reported. This entity has been recognized as a splenic non-neoplastic vascular lesion of benign evolution located in red pulp and secondary to an exaggerated stromal proliferation. The majority of the patients are asymptomatic, of incidental diagnosis, the same one that is established by Tomography or Resonance. The definitive diagnosis of this pathology was made by anatomopathological and immunhistochemical study after splenectomy.

Clinical case: The case of a 78-year-old patient was reported, with an incidental diagnosis that was made outside the institute, which shows magnetic resonance, whose report indicated a tumor of 8 by 9 cm in relation to the spleen and thrombocytopenia in the laboratory. Microscopically, it was a well-defined lesion, not encapsulated, formed by multiple angiomatoid nodules.

Evolution: Currently the patient in controls without signs or evidence of tumor recurrence, in controls in the department of digestive surgery.

Conclusion: SANT is a rare vascular entity with specific histological and immunological characteristics; formed by angiomatoid nodules constituted by capillaries, venules and sinusoids. Currently, it is considered a splenic non-neoplastic vascular lesion of benign evolution located in the red pulp and secondary to an exaggerated proliferation of the stroma. The treatment of choice of this histological entity is splenectomy.