Diagnostic challenge in gastrointestinal bleeding due to GIST: Case report

Published

2025-04-30

How to Cite

Cáceres Zuña, J. C., Ferro Gutierrez, C. A., Esparza Jurado, C., & Litardo Mosquera, A. (2025). Diagnostic challenge in gastrointestinal bleeding due to GIST: Case report. Oncology Journal (Ecuador), 35(1), 10–17. https://doi.org/10.33821/774

Issue

Section

Case Reports

Authors

DOI:

https://doi.org/10.33821/774

Keywords:

clinical case, GIST (Gastrointestinal Stromal Tumors), non-epithelial neoplasms, Kit gene mutations, gastrointestinal bleeding, hypovolemic shock, mesentery

Abstract

Introduction: Gastrointestinal stromal tumors (GISTs) are rare non-epithelial neoplasms, with an incidence of 14 to 20 cases per million people, typically occurring in individuals between 50 and 71 years of age. These tumors are primarily located in the stomach and are associated with mutations in the Kit gene. Clinical Case: A 45-year-old female patient, who developed an abdominal tumor, is presented. The tumor clinically manifested as hypovolemic shock secondary to gastrointestinal bleeding; in this case, it was located in the mesentery, which is an unusual site for this type of neoplasm. The patient was successfully treated surgically. Conclusion: This case highlights the importance of considering GISTs as a differential diagnosis in patients with acute gastrointestinal bleeding and hypovolemic shock. The mesenteric location of the tumor is an uncommon feature, underscoring the variability in the presentation of GISTs. Early detection and appropriate surgical treatment are essential for managing this pathology. Additionally, this case emphasizes the need for thorough evaluation in younger patients, despite GISTs being more common in older adults.

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Author Biographies

Juan Carlos Cáceres Zuña, Universidad Espíritu Santo

Médico posgradista de 1.er año en Medicina Interna, Hospital Clínica San Francisco - UEES, Guayaquil

Christian Arnaldo Ferro Gutierrez, Universidad Espíritu Santo

Médico posgradista de 4.o año en Medicina Interna, Hospital Clí­nica San Francisco - UEES, Guayaquil.

Christian Esparza Jurado, Hospital Clínica San Francisco

Médico especialista en Medicina Interna, Hospital Clínica San Francisco, Guayaquil.

Andrés Litardo Mosquera, Hospital Clínica San Francisco

Médico especialista en Endocrinología, Hospital Clínica San Francisco, Guayaquil.

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