Dysgerminoma in an adolescent with Down's syndrome: A case report

Abstract

Introduction: Germ cell tumors are the most prevalent ovarian malignancy in adolescents and girls; they are generally detected in early stages. The association with Down syndrome, the reason for presenting this case, is unknown.

Clinical Case: We present the case of a 13-year-old girl with Down syndrome, referred by a painful suprapubic mass with two months of evolution.

Diagnostic workshop: The extension studies detected a tumor at the pelvic level dependent on the left ovary, for which a lumpectomy was planned. The histopathological examination determined the presence of a germ cell tumor with a dysgerminoma and trophoblastic component.

Evolution: The patient was prescribed chemotherapy treatment, with favorable development at 16 months of follow-up.

Conclusion: The classic symptoms of germ cell tumors in Down syndrome are not very indicative; In most cases, it is about preserving fertility, even when girls are carriers of Down Syndrome. Follow-up, in this case, has been favorable for 16 months.