Buschke – Löwenstein Tumor

A Case Report and Review of the Literature

Additional Files

Published

2022-08-19

How to Cite

Leone, P., & Carvajal, M. F. (2022). Buschke – Löwenstein Tumor: A Case Report and Review of the Literature. Oncology Journal (Ecuador), 32(2), 253–265. https://doi.org/10.33821/619

Issue

Vol. 32 No. 2 (2022): August- November

Section

Case Reports

License

Copyright (c) 2022 Paolo Leone, Maria Fernanda Carvajal

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

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Authors

  • Paolo Leone Department of Dermatology, National Oncology Institute “Dr. Juan Tanca Marengo”, Society for the Fight Against Cancer, Solca, Guayaquil https://orcid.org/0000-0002-8892-2215
  • Maria Fernanda Carvajal Department of Dermatology, National Oncology Institute “Dr. Juan Tanca Marengo”, Society for the Fight Against Cancer, Solca, Guayaquil

DOI:

https://doi.org/10.33821/619

Keywords:

Buschke-Lowenstein Tumor, Condyloma Acuminata, Human Papillomavirus 6, Human Papillomavirus 11, Nonavalent Vaccine, Radiotherapy

Abstract

Introduction: Buschke-Lowenstein tumor (BLT) is a sexually transmitted disease caused by the human papillomavirus (HPV), described as an intermediate form between condyloma acuminata and squamous cell carcinoma. It mainly affects the genital and anorectal areas and has the capacity for malignant transformation and a high recurrence rate. Surgery is the first-line treatment.

Clinical case: We present the case of a 27-year-old male patient with warty lesions of progressive growth in the inguinal and genital areas. Through the clinical-pathological correlation, the diagnosis of BLT was reached. After discussion in a multidisciplinary committee, it was declared unresectable, and treatment with radiotherapy was resolved, in addition to therapeutic vaccination against HPV, both systemic and intralesional.

Conclusion: BLT is locally aggressive and challenging to treat, so prevention against HPV is essential. Therapeutic vaccination in conjunction with radiotherapy offered clinical improvement.

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