Prevalence and characterization of virgin women di-agnosed with cervical, endometrial and ovarian can-cer, a single center study

Original Research

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Published

2021-12-11

How to Cite

Granda Maldonado, D. R., Vicuña Freire, F. H., & Landivar Varas, X. F. (2021). Prevalence and characterization of virgin women di-agnosed with cervical, endometrial and ovarian can-cer, a single center study: Original Research. Oncology Journal (Ecuador), 31(3), 213–225. https://doi.org/10.33821/590

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Vol. 31 No. 3 (2021): December - March

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Original Articles

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Copyright (c) 2021 Doménica Romina Granda Maldonado, Fernando Humberto Vicuña Freire, Xavier Francisco Landivar Varas

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This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

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Authors

  • Doménica Romina Granda Maldonado Carrera de Medicina, Facultad de Ciencias Médicas, Universidad Católica de Santiago de Guayaquil https://orcid.org/0000-0001-9412-4685
  • Fernando Humberto Vicuña Freire Carrera de Medicina, Facultad de Ciencias Médicas, Universidad Católica de Santiago de Guayaquil
  • Xavier Francisco Landivar Varas Carrera de Medicina, Facultad de Ciencias Médicas, Universidad Católica de Santiago de Guayaquil

DOI:

https://doi.org/10.33821/590

Keywords:

Uterine Neoplasms, Uterine Cervical Neoplasms, Ovarian Neoplasms, Endometrial Neoplasms, Sexual Behavior, Parity

Abstract

Introduction: Endometrial cancer, ovarian cancer and cervical cancer are the neoplasias, within cancer of the female reproductive system, which are considered more frequent today. The appearance of gynecological cancer in virgin women shows that other causal factors of the disease must be considered, however, in our country, there is not enough documentary evidence on these cases. The objective of this study is to measure the prevalence of cervical, uterine and ovarian cancer in virgin women treated in a reference center for Gynecology Oncology in Guayaquil.

Methodology: The study is observational and cross-sectional, it was carried out at the Teodoro Maldonado Carbo Specialties Hospital, of the Ecuadorian Social Security Institute, Guayaquil-Ecuador, from January 2013 to December 2017. Patients with cervical, uterine and cervical cancer were included. ovaries divided into Group 1 (G1) Virgin women and Group 2 (G2): Women with an active sexual life. The variables were age, affected organ, comorbidities, family history of cancer, histological type, and death. The sample was non-probabilistic, census type. Analytical statistics are used, the sample divided into 2 groups is compared using Chi2. Odds Ratio is reported with a confidence interval of 95%.

Results: In G1 there were 44 cases and in G2 there were 337 cases. Which represents a prevalence of 11.55% (95% CI 11.38-11.71%). Ovarian cancer in G1 was 29/44 cases (66%) versus 95/337 cases (28.2%) in G2 P <0.0001 with OR: 4.92 (2.53-9.60). Endometrial cancer in G1 13/44 cases (29.5%) versus 54/337 cases (16%) in G2, OR 2.20 (1.08-4.47) P = 0.03. Cervical cancer in G1 2/44 cases (4.5%) and in G2 188/337 cases (55.8%) OR 0.38 (0.009-0.159) P <0.0001. Mortality in G1 was 30/44 cases in G2 it was 130/337 cases, OR 4.14 (2.12-8.08) P> 0.0001.

Conclusion: In women with no history of sexual life, there is a greater risk of ovarian and endometrial cancer and the risk of cervical cancer is decreased by 96%. The mortality of this group of women doubles due to the increased existence of ovarian and endometrial cancer.

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Author Biographies

Doménica Romina Granda Maldonado, Carrera de Medicina, Facultad de Ciencias Médicas, Universidad Católica de Santiago de Guayaquil

Médica por la Universidad Católica Santiago de Guayaquil (Ecuador, 2019).

Fernando Humberto Vicuña Freire, Carrera de Medicina, Facultad de Ciencias Médicas, Universidad Católica de Santiago de Guayaquil

Médico por la Universidad Católica Santiago de Guayaquil (Ecuador, 2019).

Xavier Francisco Landivar Varas, Carrera de Medicina, Facultad de Ciencias Médicas, Universidad Católica de Santiago de Guayaquil

Doctor en medicina y cirugía por la Universidad Católica Santiago de Guayaquil (Ecuador, 2002), Master en Genética Médica por el Instituto Superior de Ciencias Médicas de La Habana (Cuba, 2010).