Line B lymphomas: understanding their bases
Narrative Review
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Copyright (c) 2020 Esteban Homero Villa Cárdenas, Priscila Belén Cárdenas Valdez, Mónica Mercedes Valdez Cárdenas; EDITOR: Dr. Felipe Xavier Campoverde Merchán
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
DOI:
https://doi.org/10.33821/487Keywords:
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma, Antigens, CD20, Flow Cytometry, Karyotype, High-Throughput Nucleotide Sequencing, ReviewAbstract
Purpose of the review: the objective of the review is to delineate the pathophysiology of B-line lymphomas. We are looking for reports that include a description of the origin of B-lymphomas for a better understanding of this pathology, in light of advances in the different areas.
Recent Findings: The Euroflow Group has published a list of Surface Antigen Expression panels in Non-Hodgkin Lymphoma, the list of which is presented in this article.
Extract: Hematological neoplasms have had great advances in recent years in several fields, evolving from cytological identification, passing through their immunophenotypic characterization through Flow Cytometry and Immunohistochemistry and reaching molecular characterization, starting with Conventional Karyotype Techniques , continuing with in situ Immunohybridization techniques and currently with molecular identification through New Generation Sequencing. This is the reason why staging systems have also evolved, the one currently in force being the one proposed by the World Health Organization in 2016. Lymphomas constitute a heterogeneous group of hematological neoplasms with a wide spectrum of clinical presentation, originating from lymphoid precursors and affecting the various lymphoid organs. Of these, line B lymphomas are the most common, which is the reason for this review.
