Case report: Veno-Occlusive liver disease secondary to Chemotherapy in a patient with Ewing's Sarcoma.

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Published

2018-04-30

How to Cite

Nasre Nasser, R., Correa Vega, M., Colmenares Álvarez, N., & Sánchez Dugarte, M. (2018). Case report: Veno-Occlusive liver disease secondary to Chemotherapy in a patient with Ewing’s Sarcoma. Oncology Journal (Ecuador), 28(1), 34–40. https://doi.org/10.33821/262

Issue

Vol. 28 No. 1 (2018): April- July

Section

Case Reports

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Copyright (c) 2018 Raif Nasre Nasser, Magdalena Correa Vega, Norlis Colmenares Álvarez, Mariener Sánchez Dugarte

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This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

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Authors

  • Raif Nasre Nasser Instituto de Endocrinología, Metabolismo y Reproducción, Quito. https://orcid.org/0000-0002-8350-1008
  • Magdalena Correa Vega Hospital Universitario de Los Andes, Mérida – Venezuela, Servicio de Pediatría.
  • Norlis Colmenares Álvarez Hospital Materno Infantil “Samuel Darío Maldonado”, Barinas – Venezuela, Servicio de Pediatría.
  • Mariener Sánchez Dugarte Hospital Regional de Talca, Talca, Servicio de Terapia intensiva Pediátrica.

DOI:

https://doi.org/10.33821/262

Keywords:

VENO-OCCLUSIVE HEPATIC DISEASE, CYCLOPHOSPHAMID, VINCRISTINE, EWING SARCOMA, PEDIATRICS

Abstract

Introduction: Hepatic Veno-occlusive Disease or Sinusoidal Obstruction Syndrome is a clinical syndrome characterized by painful hepatomegaly, jaundice, ascites, edema and weight gain, which usually occurs as a complication of bone marrow transplantation.

Clinical Case: We describe a new case of male school age 9 with Ewing Sarcoma who had Hepatic Veno-occlusive Disease secondary to chemotherapy with cyclophosphamide and vincristine.

Evolution: We set the differential diagnosis from liver damage due to infection and autoimmune diseases through serological tests and biopsy.

Conclusion: This is the first report that describes the association between Ewing Sarcoma and Hepatic Veno-occlusive Disease.

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