Criteria for ineligibility for the use of platinums in otorhino-laryngological cancer, Guidelines 2021

Expert consensus

Published

2021-04-30

How to Cite

Moreno Ocampo, A. P., Torres Toala, F. G., Moncayo, J., Riofrío, M., Chusino, E., Loor, G., Peralta, A., Guarnizo, P., Mendoza, M., Arguello, M., & Irigoyen, P. (2021). Criteria for ineligibility for the use of platinums in otorhino-laryngological cancer, Guidelines 2021: Expert consensus. Oncology Journal (Ecuador), 31(1), 15–34. https://doi.org/10.33821/540

Issue

Section

Clinical Practice Guidelines

Authors

DOI:

https://doi.org/10.33821/540

Keywords:

Platinum compounds, Otorhinolaryngologic Diseases, Laryngeal Neoplasms, Otolaryngology, Practice Guidelines as Topic

Abstract

Introduction: the use of platinum salts in oncological pathologies is widely used, one of the concerns of health professionals is the presence of adverse events in this group of patients who are usually vulnerable, so it is necessary to generate of consensus to make an optimal selection of candidate patients for platinum-based therapies

Objective: To carry out a consensus of experts for the ineligibility for the use of points according to several criteria to carry out an optimal treatment according to the selection and categorization of patients

Health question covered by the Guide: Which patients with otorhinolringological origin cancer are not eligible for treatment with platinums?

Population: The target population is adult patients with ENT cancer.

Results: consensus was established for the ineligibility for the use of lenses on the following criteria: Age> 70 years, ECOG> 1, Involuntary weight loss> 20%, “borderline” hearing function: Grade I alterations, Neurological alterations Grade I, Renal function disorders: CrCL <60 ml / min, Hepatic impairment ? grade II Child-Pugh B, Comorbidities: diabetes, hypertension, pulmonary disorders, anemia and heart failure.Keywords:

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